Our publications
Adoptive T-cell therapy projects: CAR-T, TCR-T, TIL, CTL
Selected publications
All publications
Selected publications
All publications
6
Adoptive T-cell therapy projects: CAR-T, TCR-T, TIL, CTL
20
Selected publications
20
All publications
Adoptive T-cell therapy projects: CAR-T, TCR-T, TIL, CTL
T cell repertoire remodeling following post-transplant T cell therapy coincides with clinical response
Journal of Clinical Investigation
Selected publications
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| Name | Position | Office | Age | Start date | Salary |
|---|---|---|---|---|---|
| Tiger Nixon | System Architect | Edinburgh | 61 | 2011/04/25 | $320,800 |
| Garrett Winters | Accountant | Tokyo | 63 | 2011/07/25 | $170,750 |
| Ashton Cox | Junior Technical Author | San Francisco | 66 | 2009/01/12 | $86,000 |
| Cedric Kelly | Senior Javascript Developer | Edinburgh | 22 | 2012/03/29 | $433,060 |
| Airi Satou | Accountant | Tokyo | 33 | 2008/11/28 | $162,700 |
| Brielle Williamson | Integration Specialist | New York | 61 | 2012/12/02 | $372,000 |
| Herrod Chandler | Sales Assistant | San Francisco | 59 | 2012/08/06 | $137,500 |
| Rhona Davidson | Integration Specialist | Tokyo | 55 | 2010/10/14 | $327,900 |
| Colleen Hurst | Javascript Developer | San Francisco | 39 | 2009/09/15 | $205,500 |
| Sonya Frost | Software Engineer | Edinburgh | 23 | 2008/12/13 | $103,600 |
| Jena Gaines | Office Manager | London | 30 | 2008/12/19 | $90,560 |
| Quinn Flynn | Support Lead | Edinburgh | 22 | 2013/03/03 | $342,000 |
| Charde Marshall | Regional Director | San Francisco | 36 | 2008/10/16 | $470,600 |
| Haley Kennedy | Senior Marketing Designer | London | 43 | 2012/12/18 | $313,500 |
| Tatyana Fitzpatrick | Regional Director | London | 19 | 2010/03/17 | $385,750 |
| Michael Silva | Marketing Designer | London | 66 | 2012/11/27 | $198,500 |
| Paul Byrd | Chief Financial Officer (CFO) | New York | 64 | 2010/06/09 | $725,000 |
| Gloria Little | Systems Administrator | New York | 59 | 2009/04/10 | $237,500 |
| Bradley Greer | Software Engineer | London | 41 | 2012/10/13 | $132,000 |
| Dai Rios | Personnel Lead | Edinburgh | 35 | 2012/09/26 | $217,500 |
| Jenette Caldwell | Development Lead | New York | 30 | 2011/09/03 | $345,000 |
| Yuri Berry | Chief Marketing Officer (CMO) | New York | 40 | 2009/06/25 | $675,000 |
| Caesar Vance | Pre-Sales Support | New York | 21 | 2011/12/12 | $106,450 |
| Doris Wilder | Sales Assistant | Sydney | 23 | 2010/09/20 | $85,600 |
| Angelica Ramos | Chief Executive Officer (CEO) | London | 47 | 2009/10/09 | $1,200,000 |
| Gavin Joyce | Developer | Edinburgh | 42 | 2010/12/22 | $92,575 |
| Jennifer Chang | Regional Director | Singapore | 28 | 2010/11/14 | $357,650 |
| Brenden Wagner | Software Engineer | San Francisco | 28 | 2011/06/07 | $206,850 |
| Fiona Green | Chief Operating Officer (COO) | San Francisco | 48 | 2010/03/11 | $850,000 |
| Shou Itou | Regional Marketing | Tokyo | 20 | 2011/08/14 | $163,000 |
| Michelle House | Integration Specialist | Sydney | 37 | 2011/06/02 | $95,400 |
| Suki Burks | Developer | London | 53 | 2009/10/22 | $114,500 |
| Prescott Bartlett | Technical Author | London | 27 | 2011/05/07 | $145,000 |
| Gavin Cortez | Team Leader | San Francisco | 22 | 2008/10/26 | $235,500 |
| Martena Mccray | Post-Sales support | Edinburgh | 46 | 2011/03/09 | $324,050 |
| Unity Butler | Marketing Designer | San Francisco | 47 | 2009/12/09 | $85,675 |
| Howard Hatfield | Office Manager | San Francisco | 51 | 2008/12/16 | $164,500 |
| Hope Fuentes | Secretary | San Francisco | 41 | 2010/02/12 | $109,850 |
| Vivian Harrell | Financial Controller | San Francisco | 62 | 2009/02/14 | $452,500 |
| Timothy Mooney | Office Manager | London | 37 | 2008/12/11 | $136,200 |
| Jackson Bradshaw | Director | New York | 65 | 2008/09/26 | $645,750 |
| Olivia Liang | Support Engineer | Singapore | 64 | 2011/02/03 | $234,500 |
| Bruno Nash | Software Engineer | London | 38 | 2011/05/03 | $163,500 |
| Sakura Yamamoto | Support Engineer | Tokyo | 37 | 2009/08/19 | $139,575 |
| Thor Walton | Developer | New York | 61 | 2013/08/11 | $98,540 |
| Finn Camacho | Support Engineer | San Francisco | 47 | 2009/07/07 | $87,500 |
| Serge Baldwin | Data Coordinator | Singapore | 64 | 2012/04/09 | $138,575 |
| Zenaida Frank | Software Engineer | New York | 63 | 2010/01/04 | $125,250 |
| Zorita Serrano | Software Engineer | San Francisco | 56 | 2012/06/01 | $115,000 |
| Jennifer Acosta | Junior Javascript Developer | Edinburgh | 43 | 2013/02/01 | $75,650 |
| Cara Stevens | Sales Assistant | New York | 46 | 2011/12/06 | $145,600 |
| Hermione Butler | Regional Director | London | 47 | 2011/03/21 | $356,250 |
| Lael Greer | Systems Administrator | London | 21 | 2009/02/27 | $103,500 |
| Jonas Alexander | Developer | San Francisco | 30 | 2010/07/14 | $86,500 |
| Shad Decker | Regional Director | Edinburgh | 51 | 2008/11/13 | $183,000 |
| Michael Bruce | Javascript Developer | Singapore | 29 | 2011/06/27 | $183,000 |
| Donna Snider | Customer Support | New York | 27 | 2011/01/25 | $112,000 |
| Name | Position | Office | Age | Start date | Salary |
Multi-omics Augmented Intelligence for T-cell therapy drug development
Moonshot startup from UC Berkeley SkyDeck improves the design of T-cell therapies such as CAR-T by precisely identifying T-cell subpopulations and their immune profile
Pfizer · Novartis · UCSF · Stanford · MIT · MD Anderson Cancer Center ·
The Johns Hopkins University School of Medicine
The Johns Hopkins University School of Medicine
and the global community of 45,000 medical scientists and researchers worldwide
Trusted by teams at
"Using the platform has been extremely helpful in producing beautiful publication ready plots for visualizing how clonotypes change across different timepoints. The platform takes hours off data analysis by providing a tool to easily analyze multiple data files and run biomarker discovery in a very smooth and quick way."
— Molly B. El Alam, MPH. Research Assistant, Department of Radiation Oncology, The University of Texas M.D. Anderson
"The platform has been incredibly helpful with analyzing and interpreting our data. When I reached out with questions, Vadim (Co-Founder/ CEO ImmunoMind) was very helpful and responsive. I'm grateful to ImmunoMind for making this critical analysis program."
— Senior Researcher, TOP-5 Pharma company
"I used the platform to analyse TCR expression in RNAseq data from human skin. It is very handy even without strong prior knowledge in programming and R!"
— Irène Gallais, PhD, MD, Dermatologist in Besancon University Hospital France, affiliated to CMM, Karolinska Institute, Sweden
10+ years in T-cell biology- 100+ projects
ImmunoMind's Augmented Intelligence platform.
ImmunoMind's Augmented Intelligence platform guides translational and clinical research to improve the product's quality, safety and efficacy with single-cell precision.
T cell exhaustion and T cell heterogeneity are considered to be crucial factors at all stages of CAR-T development and manufacturing. T cell exhaustion is a dysfunctional state of T-cells arising from excessive antigen stimulation.
Heterogeneity subpopulations and CD4+/CD8+ ratio are vital attributes of CAR-T product that should be analyzed for the development of effective drugs. By using single-cell technologies, it is now possible to dive into the internal context of CAR-T products, while delineating cell subtypes and cell diversity.
Single-cell multi-omics technologies.
The platform is based on proprietary single-cell multi-omics technologies to automatically evaluate cell differentiation, estimate exhaustion rate of subpopulations and identify off-tumor targets.
Platform benefits.
Quality Control
- Evaluation of cell population differentiation
Safety
- Estimation of exhaustion rate of cell populations
- Search for novel targetable antigens
Efficacy
- Evaluation of immune cytokine profile
- Identification of off-tumor target
Partner with us.
Emerging Biotech Partnerships
Atomwise helps emerging biotechnology companies and university spin-offs accelerate their innovations with AI-based drug discovery.
Biopharma Partnerships
Atomwise partners with the world's leading pharmaceutical and biotechnology companies to transform drug discovery.
Research Partnerships
We partner with academic, government, and non-profit research institutes to democratize drug discovery with AI.