Early assessment of CAR-T cell populations is critical for improving success in later development stages. With ImmunoMind, you can evaluate CAR-T cells' activation, proliferation, cytotoxicity, senescence, and exhaustion, simultaneously comparing characteristics of several CAR-T products to help companies choose the most effective candidate.
T-cell exhaustion is a dysfunctional state of T-cells arising from excessive antigen stimulation. It is considered to be one of the critical factors at all stages of CAR-T development and manufacturing. ImmunoMind's technologies precisely evaluate CAR-T cell exhaustion, helping companies refine CAR-T products for improved efficacy.
Heterogeneity subpopulations and CD4+/CD8+ ratio are vital attributes of CAR-T products that should be analyzed to develop effective drugs. By using single-cell technologies, it is now possible to dive into the internal context of CAR-T products while delineating cell subtypes and cell diversity.
The predominance of more differentiated cells in the final CAR-T product diminishes efficacy. Identifying various differentiated subpopulations optimizes the CAR-T manufacturing process. ImmunoMind's actionable insights assist in selecting the most effective composition of a CAR-T product and allow manufacturing process modification.
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De-risk immunotherapy on the crucial discovery steps by focusing on the most efficient immunotherapy candidates.
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Focus on immunotherapy candidates that work and stratify patients for successful clinical trials.
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Study immune cell biology and discover new targets and biomarkers for immunotherapies with the AI and bioinformatics capabilities of ImmunoMind.
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